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2016

Jeffrey Gagnon, PhD

Department of Biology, Laurentian University Investigating the role of H2S in the regulation of ghrelin secretion Ghrelin, a hormone produced in the endocrine cells of the stomach, regulates several aspects of metabolic health, including appetite and energy storage. Recently, meals high in the amino acid cysteine have been shown to reduce ghrelin secretion. Foods rich…

2016

Kaitlyn McLachlan, PhD

Department of Psychology, University of Guelph Evaluating novel neurobiomarkers in the identification of adults with FASD using portable eye tracking and EEG technology Individuals with fetal alcohol spectrum disorder (FASD) are overrepresented in the criminal justice system. There is an urgent need to identify neurobiomarkers of FASD and individuals at risk in order to reduce…

2016

Noam Miller, PhD

Department of Psychology, Wilfrid Laurier University Exploring neural mechanisms of social behavior using zebrafish (Danio rerio) This research study uses zebrafish, a small freshwater species of fish commonly used in genetic and developmental research, to explore the mechanisms of social behavior. Zebrafish spend the majority of their time in groups and have complex social interactions,…

2016

Roxane Paulin, PhD

Department of Medicine, Université Laval Targeting ErbB2 by TAK-165 reverses pulmonary hypertension in vitro and in vivo In pulmonary hypertension (high blood pressure in the lungs), cells forming the walls of arteries in the lungs proliferate like cancer cells, narrowing the arteries and making it difficult for blood to pass through. There is also evidence…

2015

Jeffrey Chen, PhD

VIDO-InterVac, University of Saskatchewan Towards a next generation of superior BCG tuberculosis vaccines Tuberculosis is a serious global health problem, with one-third of the world’s population having been infected by the infectious agent, Mycobacterium tuberculosis. The only available tuberculosis vaccine, live M. bovis BCG vaccine, has an excellent record in protecting infants, but works poorly…

2015

Petra Kienesberger, PhD

Department of Biochemistry and Molecular Biology, Dalhousie University Role of the adipokine autotaxin in obesity-associated insulin resistance Insulin resistance, a major complication of obesity, is a condition where tissues such as skeletal muscle become unresponsive to the blood sugar-lowering hormone insulin. Insulin resistance can lead to type 2 diabetes, which is associated with a shorter…

2015

Morgan Langille, PhD

Department of Pharmacology, Dalhousie University Design and implementation of a human microbiome interaction database It is becoming increasingly apparent that the microbes living on and in our bodies, called the human microbiome, are important for human health. These microbes help with the digestion of food, defend against unwanted pathogens, stimulate and keep our immune systems…

2015

Joon Lee, PhD

School of Public Health and Health Systems, University of Waterloo Personalized predictive analytics based on electronic medical data and patient similarity metrics As hospitals and doctors’ offices in Canada rapidly adopt electronic medical records (EMRs), the enormous clinical value of ever-increasing EMR data is receiving the spotlight. In particular, massive EMR data can facilitate personalized…

2015

Catherine Martel, PhD

Department of Medicine, Université de Montréal/ Montreal Heart Institute Research Centre Lymphatic vessel function in atherosclerosis High blood cholesterol is an important risk factor for cardiovascular diseases such as atherosclerosis. High-density lipoprotein (HDL) is called “good cholesterol” because it transports cholesterol away from tissues, such as the blood vessel walls, carrying cholesterol through the blood…