2017

Jennifer Gordon, PhD

Department of Psychology, University of Regina HPA axis dysregulation in the etiology of perimenopausal depression Women are 2-4 times more likely to develop depression during perimenopause, the menopause transition phase, than at any other time in their lives. Dr Gordon proposes that increased estrogen fluctuation during this phase may trigger dysregulation of the hypothalamic-pituitary-adrenal (HPA)…

2017

Florian Bentzinger, PhD

Department of Pharmacology-Physiology, Université de Sherbrooke Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called “stem cell niche” controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help in…

2016

Jeanette Boudreau, PhD

Department of Microbiology and Immunology, Dalhousie University Directing natural killer cell cytotoxicity to the tumour’s susceptibilities Natural killer (NK) cells are white blood cells that kill tumours. The potential of each NK cell to kill tumours is counterbalanced by its ability to be inhibited by healthy cells through its inhibitory receptors. Dr Boudreau aims to…

2016

Jeffrey Gagnon, PhD

Department of Biology, Laurentian University Investigating the role of H2S in the regulation of ghrelin secretion Ghrelin, a hormone produced in the endocrine cells of the stomach, regulates several aspects of metabolic health, including appetite and energy storage. Recently, meals high in the amino acid cysteine have been shown to reduce ghrelin secretion. Foods rich…

2016

Kaitlyn McLachlan, PhD

Department of Psychology, University of Guelph Evaluating novel neurobiomarkers in the identification of adults with FASD using portable eye tracking and EEG technology Individuals with fetal alcohol spectrum disorder (FASD) are overrepresented in the criminal justice system. There is an urgent need to identify neurobiomarkers of FASD and individuals at risk in order to reduce…

2016

Noam Miller, PhD

Department of Psychology, Wilfrid Laurier University Exploring neural mechanisms of social behavior using zebrafish (Danio rerio) This research study uses zebrafish, a small freshwater species of fish commonly used in genetic and developmental research, to explore the mechanisms of social behavior. Zebrafish spend the majority of their time in groups and have complex social interactions,…

2016

Roxane Paulin, PhD

Department of Medicine, Université Laval Targeting ErbB2 by TAK-165 reverses pulmonary hypertension in vitro and in vivo In pulmonary hypertension (high blood pressure in the lungs), cells forming the walls of arteries in the lungs proliferate like cancer cells, narrowing the arteries and making it difficult for blood to pass through. There is also evidence…

2015

Jeffrey Chen, PhD

VIDO-InterVac, University of Saskatchewan Towards a next generation of superior BCG tuberculosis vaccines Tuberculosis is a serious global health problem, with one-third of the world’s population having been infected by the infectious agent, Mycobacterium tuberculosis. The only available tuberculosis vaccine, live M. bovis BCG vaccine, has an excellent record in protecting infants, but works poorly…