Department of Biomedical Sciences, University of Guelph Nicotinic receptor signaling in a mouse model of Fetal Alcohol Spectrum Disorder Chronic prenatal exposure to alcohol can produce a spectrum of adverse effects known collectively as Fetal Alcohol Spectrum Disorder (FASD). Although deficits in attention rank among the most common and persistent components of FASD, mechanisms underlying…
Martin Lévesque, PhD
Department of Psychiatry and Neurosciences, Université Laval Molecular mechanisms of axon guidance mediated by PlexinC1 in dopamine neuron axonal projections Degeneration of midbrain dopaminergic neurons (mDA) is the principal cause of Parkinson’s disease. Grafts of dopaminergic neurons newly generated from stem cells represent a promising therapeutic avenue. However, inappropriate re-innervation of the grafted neurons represents…