By Krista Lamb – While we often think of obesity as a condition related to diet and exercise, the reality is that it’s much more complicated than just those two things. Many people who develop obesity will do so because of a myriad of complex factors, including metabolic or genetic issues. They may, in turn,…
Gareth Lim, PhD
CRCHUM, Department of Medicine, Université de Montréal Evaluating the therapeutic potential of 14-3-3ζ for the treatment of obesity Approximately 25% of Canadians are either overweight or obese. Current therapies have only modest success in reducing body weight, and surprisingly, none directly target fat cells, which are key in the development of obesity.
Catherine Larochelle, MD PhD
CRCHUM, Department of Neurosciences, Université de Montréal Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons vulnerable.…
