2017

Julien van Grevenynghe, PhD

Department of Infectious diseases, immunity, cancer and epidemiology, INRS – Institut Armand-Frappier and the Université du Québec Autophagy regulates CD8 T-cell killing activity during chronic HIV-1 infection Autophagy, a natural self-destructive process in cells, eliminates some viruses from cells, and also plays a role in shaping functions of T cells, a primary part of the…

2017

Adena Scheer, MD

Department of Surgery, St Michael’s Hospital, Li Ka Shing Knowledge Institute, and the University of Toronto Cross-cultural communications in breast cancer treatment Among minorities, disparities in breast cancer treatments have been demonstrated across the developed world and have been associated with worse cancer outcomes. In Canada we have the highest rate of foreign-born individuals among…

2017

Gareth Lim, PhD

CRCHUM, Department of Medicine, Université de Montréal Evaluating the therapeutic potential of 14-3-3ζ for the treatment of obesity Approximately 25% of Canadians are either overweight or obese. Current therapies have only modest success in reducing body weight, and surprisingly, none directly target fat cells, which are key in the development of obesity.

2017

Catherine Larochelle, MD PhD

CRCHUM, Department of Neurosciences, Université de Montréal Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons vulnerable.…

2017

Jennifer Gordon, PhD

Department of Psychology, University of Regina HPA axis dysregulation in the etiology of perimenopausal depression Women are 2-4 times more likely to develop depression during perimenopause, the menopause transition phase, than at any other time in their lives. Dr Gordon proposes that increased estrogen fluctuation during this phase may trigger dysregulation of the hypothalamic-pituitary-adrenal (HPA)…

2017

Florian Bentzinger, PhD

Department of Pharmacology-Physiology, Université de Sherbrooke Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called “stem cell niche” controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help in…

Grant Impact

Imogen R Coe, PhD

Imogen Coe, Founding Dean of the Faculty of Science at Ryerson University, is internationally recognized for her research in the cell biology and biochemistry of membrane transport proteins. Dr Coe received a Banting Research Foundation grant in 1998, while at York University, to study the influence of steroid hormones on the uptake of a class…

Grant Impact

Adolfo J. de Bold, OC PhD FRSC

Adolfo de Bold is a cardiovascular researcher, best known for his discovery of atrial natriuretic factor (ANF), a polypeptide hormone secreted by heart muscle cells. He was funded by the Banting Research Foundation in 1980 for his studies on storage granules in atrial heart cells. The resulting discovery and isolation of atrial natriuretic factor changed…