2017

Catherine Larochelle, MD PhD

CRCHUM, Department of Neurosciences, Université de Montréal Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons vulnerable.…

2017

Jennifer Gordon, PhD

Department of Psychology, University of Regina HPA axis dysregulation in the etiology of perimenopausal depression Women are 2-4 times more likely to develop depression during perimenopause, the menopause transition phase, than at any other time in their lives. Dr Gordon proposes that increased estrogen fluctuation during this phase may trigger dysregulation of the hypothalamic-pituitary-adrenal (HPA)…

2017

Florian Bentzinger, PhD

Department of Pharmacology-Physiology, Université de Sherbrooke Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called “stem cell niche” controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help in…

Grant Impact

Imogen R Coe, PhD

Imogen Coe, Founding Dean of the Faculty of Science at Ryerson University, is internationally recognized for her research in the cell biology and biochemistry of membrane transport proteins. Dr Coe received a Banting Research Foundation grant in 1998, while at York University, to study the influence of steroid hormones on the uptake of a class…

Grant Impact

Adolfo J. de Bold, OC PhD FRSC

Adolfo de Bold is a cardiovascular researcher, best known for his discovery of atrial natriuretic factor (ANF), a polypeptide hormone secreted by heart muscle cells. He was funded by the Banting Research Foundation in 1980 for his studies on storage granules in atrial heart cells. The resulting discovery and isolation of atrial natriuretic factor changed…

Grant Impact

Janet Rossant, CC PhD FRS FRSC

Janet Rossant is a world-renowned expert in developmental biology. Funded by the Banting Research Foundation in 1983, while at Brock University, for her early research in developmental biology, she has become a global leader in understanding the role of genes in embryo development. Her work has been fundamental in the development of human pluripotent stem…

2016

Jeanette Boudreau, PhD

Department of Microbiology and Immunology, Dalhousie University Directing natural killer cell cytotoxicity to the tumour’s susceptibilities Natural killer (NK) cells are white blood cells that kill tumours. The potential of each NK cell to kill tumours is counterbalanced by its ability to be inhibited by healthy cells through its inhibitory receptors. Dr Boudreau aims to…