Department of Biomedical Sciences, University of Guelph Nicotinic receptor signaling in a mouse model of Fetal Alcohol Spectrum Disorder Chronic prenatal exposure to alcohol can produce a spectrum of adverse effects known collectively as Fetal Alcohol Spectrum Disorder (FASD). Although deficits in attention rank among the most common and persistent components of FASD, mechanisms underlying…
David Chatenet, PhD
Centre INRS–Institut Armand-Frappier Design and synthesis of peptide inhibitors of PqsE as novel antibacterial therapeutics Pseudomonas aeruginosa (Pa), a prevalent opportunistic human pathogen responsible for morbidity and mortality among individuals suffering from cystic fibrosis, is notorious for its high resistance to antibiotic treatments.
Margaret K Hahn, MD PhD
Centre for Addiction and Mental Health Central insulin to prevent olanzapine-induced adiposity: a rodent model Atypical antipsychotic (AAP) medications, the mainstay treatment for psychosis and schizophrenia, are defined by weight gain and metabolic problems that likely contribute to a 2-fold increase in cardiovascular (CV) deaths in this population.
Pierre-Yves Lozach, PhD
Centre INRS – Institut Armand-Frappier Bunyavirus entry into mammalian cells Bunyaviridae is a large family of viruses mainly transmitted by arthropods such as mosquitos and ticks. Many bunyaviruses are important pathogens in humans and livestock. Due to their mode of transmission, they are considered emerging agents of diseases. Unfortunately, bunyaviruses are understudied, which has contributed to…
Dave Richard, PhD
Département de microbiologie-infectiologie et d’immunologie, Université Laval Protein trafficking to the apical complex of the malaria parasite Malaria is one of the world’s most common infectious diseases, with approximately 274 million cases each year and 1 million deaths, and thus represents one of the most devastating global public health problems.
Marie-Ève Tremblay, PhD
Département de médecine moléculaire, Université Laval Microglial relationships with synaptic elements in Alzheimer’s disease A series of recent discoveries have challenged our view of microglia, the brain immune cells, showing unexpected roles in the active maintenance of neuronal circuits throughout the lifespan. Contributing to this nascent field of investigation, this project aims at exploring the…